Ehrlichiosis - Revision history

Rossdonaldson1: /* Background */

2025-07-30T18:11:33Z

Background

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	[[File:Ehrlichia.jpg\|thumb\|Reported incidence rate of Ehrlichia chaffeensis ehrlichiosis 2000–2013 (per 1,000,000 persons per year).]]		[[File:Ehrlichia.jpg\|thumb\|Reported incidence rate of Ehrlichia chaffeensis ehrlichiosis 2000–2013 (per 1,000,000 persons per year).]]
	[[File:Lone Star Tick.jpg\|thumb\|Lone Star Tick (preserved]]		[[File:Lone Star Tick.jpg\|thumb\|Lone Star Tick (preserved]]
			[[File:Rr6502a1f13.gif\|thumb\|Approximate U.S. distribution of Amblyomma americanum (lone star tick).]]
	*Bacterial infection of the family Anaplasmataceae common in mammals such as cattle, dogs, sheep, goats, and horses<ref>CDC. Ehrlichiosis. http://www.cdc.gov/ehrlichiosis.</ref>		*Bacterial infection of the family Anaplasmataceae common in mammals such as cattle, dogs, sheep, goats, and horses<ref>CDC. Ehrlichiosis. http://www.cdc.gov/ehrlichiosis.</ref>
	*Spread by the Lonestar tick (Amblyomma americanum)		*Spread by the Lonestar tick (Amblyomma americanum)

2025-07-30T18:09:45Z

Background

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	==Background==		==Background==
			[[File:Ehrlichia.jpg\|thumb\|Reported incidence rate of Ehrlichia chaffeensis ehrlichiosis 2000–2013 (per 1,000,000 persons per year).]]
			[[File:Lone Star Tick.jpg\|thumb\|Lone Star Tick (preserved]]
	*Bacterial infection of the family Anaplasmataceae common in mammals such as cattle, dogs, sheep, goats, and horses<ref>CDC. Ehrlichiosis. http://www.cdc.gov/ehrlichiosis.</ref>		*Bacterial infection of the family Anaplasmataceae common in mammals such as cattle, dogs, sheep, goats, and horses<ref>CDC. Ehrlichiosis. http://www.cdc.gov/ehrlichiosis.</ref>
	*Spread by the Lonestar tick (Amblyomma americanum)		*Spread by the Lonestar tick (Amblyomma americanum)
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	**People often unaware they are bitten with case fatality rate of approximately 1.8%<ref>CDC http://www.cdc.gov/ehrlichiosis/stats/</ref>		**People often unaware they are bitten with case fatality rate of approximately 1.8%<ref>CDC http://www.cdc.gov/ehrlichiosis/stats/</ref>
	**More severe disease in immunocompromised patients ([[HIV]], Elderly, '''[[Asplenic]]''')		**More severe disease in immunocompromised patients ([[HIV]], Elderly, '''[[Asplenic]]''')

	~~[[File:Lone Star Tick.jpg\|thumb\|Lone Star Tick (preserved]]~~

	==Clinical Features==		==Clinical Features==

2025-07-30T18:03:58Z

Disposition

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	==Disposition==		==Disposition==
	*~~most~~ cases ~~of Ehrlichiosis~~ are treated as an outpatient		*Most cases are treated as an outpatient

	==See also==		==See also==

2025-07-29T18:11:16Z

Evaluation

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	*'''Enzyme Immunoassay'''		*'''Enzyme Immunoassay'''
	**Qualitative tests, not quantitative		**Qualitative tests, not quantitative
	*Leukopenia, ~~elevated transaminases~~, ~~thrombocytopenia~~ often present		*Leukopenia, thrombocytopenia, and transaminitis often present

	==Management==		==Management==

2019-09-30T23:54:18Z

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	***Connecticut (8.1 to 15.9 cases per million)		***Connecticut (8.1 to 15.9 cases per million)
	**People often unaware they are bitten with case fatality rate of approximately 1.8%<ref>CDC http://www.cdc.gov/ehrlichiosis/stats/</ref>		**People often unaware they are bitten with case fatality rate of approximately 1.8%<ref>CDC http://www.cdc.gov/ehrlichiosis/stats/</ref>
	**More severe disease in immunocompromised patients ([[HIV]], Elderly, '''Asplenic''')		**More severe disease in immunocompromised patients ([[HIV]], Elderly, '''[[Asplenic]]''')

	[[File:Lone Star Tick.jpg\|thumb\|Lone Star Tick (preserved]]		[[File:Lone Star Tick.jpg\|thumb\|Lone Star Tick (preserved]]

2019-01-18T22:45:31Z

Management

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	==Management==		==Management==
	~~===Doxycycline===~~		{{Ehrlichiosis antibiotics}}
	*Adults: 100mg PO/IV BID x 14 days
	*Children: (under 45 kg): 2.2mg/kg body weight twice a day

	==Disposition==		==Disposition==

2018-01-28T09:36:07Z

Clinical Features

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	==Clinical Features==		==Clinical Features==
	*Variable spectrum of severity of disease		*Variable spectrum of severity of disease
	*[[Fever]]/chills, malaise, myalgias		*[[Fever]]/chills (abrupt onset), malaise, myalgias
	*[[Headache]]		*[[Headache]]
	*[[Nausea/vomiting]], [[diarrhea]]		*[[Nausea/vomiting]], [[diarrhea]]

2017-08-31T21:00:28Z

Clinical Features

2017-08-31T21:00:15Z

Clinical Features

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	==Clinical Features==		==Clinical Features==
	*Fever, chills, headache, malaise, myalgias, nausea, vomiting, diarrhea, conjunctival injection
	**Up to 60% of children may have a rash (30% of adults)
	*Variable spectrum of severity of disease		*Variable spectrum of severity of disease
			*[[Fever]]/chills, malaise, myalgias
			*[[Headache]]
			*[[Nausea/vomiting]], [[diarrhea]]
			*Conjunctival injection
			*[[Rash]][
			**Up to 60% in children, 30% of adults

	==Differential Diagnosis==		==Differential Diagnosis==

2017-08-23T12:32:02Z

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	*Spread by the Lonestar tick (Amblyomma americanum)		*Spread by the Lonestar tick (Amblyomma americanum)
	**Eastern seaboard from Florida to Maine and as far west as Iowa and Texas		**Eastern seaboard from Florida to Maine and as far west as Iowa and Texas
			**States with the highest incidence:<ref>Sexton DJ and McClain MT. Human ehrlichiosis and anaplasmosis. UpToDate.</ref>
			***Rhode Island (36.5 cases per million)
			***Minnesota (3.9 to 12.3 cases per million)
			***Connecticut (8.1 to 15.9 cases per million)
	**People often unaware they are bitten with case fatality rate of approximately 1.8%<ref>CDC http://www.cdc.gov/ehrlichiosis/stats/</ref>		**People often unaware they are bitten with case fatality rate of approximately 1.8%<ref>CDC http://www.cdc.gov/ehrlichiosis/stats/</ref>
	**More severe disease in immunocompromised patients ([[HIV]], Elderly, '''Asplenic''')		**More severe disease in immunocompromised patients ([[HIV]], Elderly, '''Asplenic''')
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	*Fever, chills, headache, malaise, myalgias, nausea, vomiting, diarrhea, conjunctival injection		*Fever, chills, headache, malaise, myalgias, nausea, vomiting, diarrhea, conjunctival injection
	**Up to 60% of children may have a rash (30% of adults)		**Up to 60% of children may have a rash (30% of adults)
			*Variable spectrum of severity of disease

	==Differential Diagnosis==		==Differential Diagnosis==