CMV colitis: Difference between revisions
Ostermayer (talk | contribs) (Created page with "==Background== ==Clinical Presentation== ==Differential Diagnosis== ==Diagnosis== ==Management== ==Disposition== {{CMV colitis treatment}} ==See Also== ==External Links=...") |
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== | ==Background== <!--T:1--> | ||
<!--T:2--> | |||
*CMV is part of the Herpesviridae family | |||
*50-80% of the world's population is seropositive for CMV | |||
*Causes a mild or undetectable infection in immunocompetent hosts | |||
*Severe systemic illness is found in immunosuppressed hosts | |||
== | ==Clinical Features== <!--T:3--> | ||
== | <!--T:4--> | ||
*[[Special:MyLanguage/Fever|Fever]] | |||
*Anorexia | |||
*Malaise | |||
*[[Special:MyLanguage/Abdominal pain|Abdominal pain]], Abdominal distention, [[Special:MyLanguage/constipation|constipation]] | |||
*[[Special:MyLanguage/Nausea/vomiting|Nausea/vomiting]] | |||
*Chronic watery [[Special:MyLanguage/diarrhea|diarrhea]] | |||
*[[Special:MyLanguage/rectal bleeding|Bloody diarrhea]] | |||
*Worsening symptoms of [[Special:MyLanguage/inflammatory bowel disease|inflammatory bowel disease]] | |||
*Weight loss | |||
*[[Special:MyLanguage/Dehydration|Dehydration]] | |||
==Differential Diagnosis== <!--T:5--> | |||
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{{Colitis DDX}} | |||
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{{CMV types}} | |||
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==Evaluation== <!--T:6--> | |||
==Management== <!--T:7--> | |||
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{{CMV colitis treatment}} | {{CMV colitis treatment}} | ||
==See Also== | <translate> | ||
==Disposition== <!--T:8--> | |||
==See Also== <!--T:9--> | |||
<!--T:10--> | |||
*[[Special:MyLanguage/Cytomegalovirus (CMV) infection|Cytomegalovirus (CMV) infection]] | |||
==External Links== <!--T:11--> | |||
== | ==References== <!--T:12--> | ||
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<references/> | <references/> | ||
[[Category:ID]] [[Category:GI]] | |||
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Latest revision as of 12:25, 7 January 2026
Background
- CMV is part of the Herpesviridae family
- 50-80% of the world's population is seropositive for CMV
- Causes a mild or undetectable infection in immunocompetent hosts
- Severe systemic illness is found in immunosuppressed hosts
Clinical Features
- Fever
- Anorexia
- Malaise
- Abdominal pain, Abdominal distention, constipation
- Nausea/vomiting
- Chronic watery diarrhea
- Bloody diarrhea
- Worsening symptoms of inflammatory bowel disease
- Weight loss
- Dehydration
Differential Diagnosis
Colitis
- Viral gastroenteritis
- Bacterial gastroenteritis
- Campylobacter infections
- Clostridium difficile colitis
- Colon cancer
- Crohn disease
- Cryptosporidiosis
- Mycobacterium Avium-Intracellulare
- Toxic megacolon
- Ulcerative colitis
- Ischemic bowel disease (e.g. mesenteric ischemia, strangulated hernia)
- Pseudomembranous enterocolitis
- Lymphoma
- Ileocecal amebiasis
- Sarcoidosis
- Yersinia
- Campylobacter
CMV Diseases
Evaluation
Management
- Ganciclovir 5mg/kg IV q12hrs x 21 days (or until resolution of symptoms)
- Foscarnet 90mg/kg IV q12hrs daily x 21 days (or until resolution of symptoms)
Disposition
See Also